Grants Awarded

Grants
All
  • All
  • ECD
  • HLH/FEL/FHL
  • JXG
  • LCH
  • Rare Histiocytic Disorders and Other Topics
  • RDD

Defining the pathophysiology of HLH in Hematologic Malignancies

Principal Investigator: Dr. Michael Jordan Cincinnati Children’s Hospital Medical Center Cincinatti, OH Date of Award: December 2022 Amount…

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Defining and Testing the Hyperinflammatory Immune Synapse

Principal Investigator: Dr. Scott Canna Children’s Hospital of Philadelphia Philadelphia, PA Date of Award: December 2022 Amount…

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Immunoproteasome inhibition as a novel therapy for hemophagocytic lymphohistiocytosis (HLH)

Principal Invesigator: Dr. Kim Nichols St. Jude Children’s Research Hospital Memphis, TN Date of Award: December 2022…

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A Study of the Spectrum of Visual Function and Choroidal Structure in Patients with Histiocytosis

Principal Investigator:  Dr. Jasmine Francis Memorial Sloan Kettering Cancer Center New York City, NY USA   Date…

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Modeling Langerhans cell Histiocytosis with patient-derived iPSCs

Principal Investigator Dr. Giulio Abagnale St.Anna Children’s Cancer Research Institute Vienna, Austria Date of Award December 2021…

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Role of the immune checkpoint TIM-3 in the pathogenesis of non-classical HLH

Principal Investigator Dr. Fernando Sepulveda Imagine Institute Paris, FR Date of Award December 2021 Amount of Award…

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Identifying novel CSF Biomarkers for the Diagnosis of Isolated CNS Hemophagocytic Lymphohistiocytosis

Principal Investigator Dr. Sharat Chandra Cincinnati Children’s Hospital Medical Center Cincinnati, Ohio USA Date of Award December…

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2020 Grant Cycle

Due to COVID-19 slowing down research and hindering access to laboratories in the Spring of 2020, the…

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Excessive IL-10 Potentiates IL-18 to Cooperatively Drive Severe Secondary HLH/MAS-like Disease and Hyper-inflammaphagocytic Macrophage Polarization in Mouse Models.

Gang Huang Cincinnati Children’s Hospital Medical Center, Cincinnati, OH USA

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Transcriptional dysregulation of myeloid cells with MAP kinase pathway mutations

Matthew Collin Newcastle University, Newcastle upon Tyne, UK

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