I am...
- All
- HLH/FEL/FHL
- LCH
- Rare Histiocytic Disorders and Other Topics
The use of a newly generated murine model to determine the broad role of STXBP2 in FHL5 pathogenesis
Principal Investigator Fernando Sepulveda, Ph.D. Imagine Institute Paris, France Date of Award December 2016 Amount of Award…
HIF-1α Signaling is a Central Pathobiologic Mediator of Hemophagocytic Lymphohistiocytosis
Principal Investigator Gang Huang, Ph.D. Children’s Hospital Medical Center Cincinnati, OH USA Date of Award December 2016…
Genetic Defects in Cytolysis in Patients with Macrophage Activation Syndrome Enrolled in a Clinical Trial to Explore Interleukin-1 Blockage Therapy
Principal Investigator Randy Cron, M.D., Ph.D. University of Alabama at Birmingham Birmingham, AL USA Date of Award…
Innate T cells in Langerhan’s Cell Histiocytosis
Principal Investigator Stuart Berzins, Ph.D. Federation University Australia Ballarat, Victoria, Australia Date of Award December 2016 Amount…
MEK Inhibition in the Therapy of Histiocytic Neoplasms
Principal Investigator Omar Abdel-Wahab, MD Memorial Sloan Kettering Cancer Center New York, New York USA Date of…
Identification of Molecular Mechanisms Underlying Defective Cytotoxic Lymphocyte Function in Chediak-Higashi Syndrome, a Histiocytic Lysosomal Storage Disorder with Immunodeficiency
Principal Investigator Konrad Krzewski, PhD National Institute of Allergy and Infectious Diseases, National Institutes of Health Rockville,…
Genetic Dissection of the Exocytic Machinery in Cytotoxic Lymphocytes
Principal Investigator Matthias Voss, PhD Karolinska Institutet Stockholm, Sweden Date of Award December 2015 Amount of…
Deciphering the Underlying Molecular Defects in CTL and NK Cell Cytotoxicity in FHL Patients
Principal Investigator Claudio Giraudo, PhD The Children’s Hospital of Philadelphia University of Pennsylvania Philadelphia, Pennsylvania USA Date…
The Interplay of NOTCH and MAPK Pathway in LCH
Principal Investigator Raphaela Schwentner, MSc, PhD Children’s Cancer Research Institute Vienna, Austria Date of Award December…
LCH-IV Clinical Trial – Stratum I Patient Registration Reimbursement for North American Institutions
Principal Investigator Carlos Rodriguez-Galindo, MD St. Jude Children’s Research Hospital Memphis, Tennessee USA Date of Award…