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- All
- HLH/FEL/FHL
- LCH
- Rare Histiocytic Disorders and Other Topics
Defining the pathophysiology of HLH in Hematologic Malignancies
Principal Investigator: Dr. Michael Jordan Cincinnati Children’s Hospital Medical Center Cincinatti, OH Date of Award: December 2022 Amount…
Defining and Testing the Hyperinflammatory Immune Synapse
Principal Investigator: Dr. Scott Canna Children’s Hospital of Philadelphia Philadelphia, PA Date of Award: December 2022 Amount…
Immunoproteasome inhibition as a novel therapy for hemophagocytic lymphohistiocytosis (HLH)
Principal Invesigator: Dr. Kim Nichols St. Jude Children’s Research Hospital Memphis, TN Date of Award: December 2022…
Role of the immune checkpoint TIM-3 in the pathogenesis of non-classical HLH
Principal Investigator Dr. Fernando Sepulveda Imagine Institute Paris, FR Date of Award December 2021 Amount of Award…
Identifying novel CSF Biomarkers for the Diagnosis of Isolated CNS Hemophagocytic Lymphohistiocytosis
Principal Investigator Dr. Sharat Chandra Cincinnati Children’s Hospital Medical Center Cincinnati, Ohio USA Date of Award December…
Excessive IL-10 Potentiates IL-18 to Cooperatively Drive Severe Secondary HLH/MAS-like Disease and Hyper-inflammaphagocytic Macrophage Polarization in Mouse Models.
Gang Huang Cincinnati Children’s Hospital Medical Center, Cincinnati, OH USA
Use of a Response-Adapted Ruxolitinib-Containing Regimen for the Treatment of Hemophagocytic Lymphohistiocytosis
Melissa Hines St Jude Children’s Research Hospital, Memphis, TN USA
Understanding the role of Epstein Barr virus in Hemophagocytic Lymphohistiocytosis
Principal Investigator Claire Shannon-Lowe The University of Birmingham Birmingham, United Kingdom Date of Award December 2018 Amount of…
Unbiased profiling of the hemophagocytic lymphohistiocytic syndrome by high-throughput single-cell transcriptomic analysis
Principal Investigator Fernando Sepulveda INSERM DR Paris 5 Paris, France Date of Award December 2018 Amount of Award…
The mechanisms of cytotoxic granule exocytosis underlying hemophagocytic lymphohistiocytosis
Principal Investigator Shuzo Sugita University Health Network Toronto, ON Canada Date of Award December 2018 Amount of Award…