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- ECD
- HLH/FEL/FHL
- JXG
- LCH
- Rare Histiocytic Disorders and Other Topics
- RDD
Mechanism of Interferon Gamma Induced Liver Sinusoidal Endothelial Cell Disruption in Familial Hemophagocytic Lymphohistiocytosis Hepatitis
Principal Investigator: Tamir Diamond Children’s Hospital of Philadelphia, Philadelphia, PA USA Date of Award: December 2025 Amount…
Evaluation of the Bromodomain and Extra Terminal (BET) Domain Activity as an actionable Target in Hemophagocytic Lymphohistiocytosis (HLH)
Principal Investigator: Polina Shindiapina The Ohio State University, Ohio, USA Date of Award: December 2025 Amount of Award:…
Validation and Implementation of a Novel Tool for Predicting Pathogenicity of Variants of Uncertain Significance in Familial Hemophagocytic Lymphohistiocytosis Genes
Principal Investigator: Kim Nichols St. Jude Children’s Hospital, Memphis,Tennesse,USA Date of Award: December 2024 Amount of Award:…
Prime editing-based correction of UNC13D
Principal Investigator: Dr. Toni Cathomen Medical Center – University of Freiburg Breisgau, Germany Date of Award: December…
Evaluation of protein arginine methyltransferase 5 (PRMT5) as an actionable target in hemophagocytic lymphohistiocytosis (HLH)
Principal Investigator: Polina Shindiapina Ohio State University Columbus, OH USA Date of Award: December 2023 Amount of Award: $50,000…
DOCK Genes: Novel Risk Alleles for Cytokine Storm Syndrome
Principal Investigator: Randy Cron University of Alabama at Birmingham Brimingham, AL USA Date of Award: December 2023 Award Amount:…
Defining the pathophysiology of HLH in Hematologic Malignancies
Principal Investigator: Dr. Michael Jordan Cincinnati Children’s Hospital Medical Center Cincinatti, OH Date of Award: December 2022 Amount…
Defining and Testing the Hyperinflammatory Immune Synapse
Principal Investigator: Dr. Scott Canna Children’s Hospital of Philadelphia Philadelphia, PA Date of Award: December 2022 Amount…
Immunoproteasome inhibition as a novel therapy for hemophagocytic lymphohistiocytosis (HLH)
Principal Invesigator: Dr. Kim Nichols St. Jude Children’s Research Hospital Memphis, TN Date of Award: December 2022…
Role of the immune checkpoint TIM-3 in the pathogenesis of non-classical HLH
Principal Investigator Dr. Fernando Sepulveda Imagine Institute Paris, FR Date of Award December 2021 Amount of Award…