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- HLH/FEL/FHL
- LCH
- Rare Histiocytic Disorders and Other Topics
- RDD
Evaluation of protein arginine methyltransferase 5 (PRMT5) as an actionable target in hemophagocytic lymphohistiocytosis (HLH)
Principal Investigator: Polina Shindiapina Ohio State University Columbus, OH USA Date of Award: December 2023 Amount of Award: $50,000…
DOCK Genes: Novel Risk Alleles for Cytokine Storm Syndrome
Principal Investigator: Randy Cron University of Alabama at Birmingham Brimingham, AL USA Date of Award: December 2023 Award Amount:…
Defining the pathophysiology of HLH in Hematologic Malignancies
Principal Investigator: Dr. Michael Jordan Cincinnati Children’s Hospital Medical Center Cincinatti, OH Date of Award: December 2022 Amount…
Defining and Testing the Hyperinflammatory Immune Synapse
Principal Investigator: Dr. Scott Canna Children’s Hospital of Philadelphia Philadelphia, PA Date of Award: December 2022 Amount…
Immunoproteasome inhibition as a novel therapy for hemophagocytic lymphohistiocytosis (HLH)
Principal Invesigator: Dr. Kim Nichols St. Jude Children’s Research Hospital Memphis, TN Date of Award: December 2022…
Role of the immune checkpoint TIM-3 in the pathogenesis of non-classical HLH
Principal Investigator Dr. Fernando Sepulveda Imagine Institute Paris, FR Date of Award December 2021 Amount of Award…
Identifying novel CSF Biomarkers for the Diagnosis of Isolated CNS Hemophagocytic Lymphohistiocytosis
Principal Investigator Dr. Sharat Chandra Cincinnati Children’s Hospital Medical Center Cincinnati, Ohio USA Date of Award December…
Excessive IL-10 Potentiates IL-18 to Cooperatively Drive Severe Secondary HLH/MAS-like Disease and Hyper-inflammaphagocytic Macrophage Polarization in Mouse Models.
Gang Huang Cincinnati Children’s Hospital Medical Center, Cincinnati, OH USA
Use of a Response-Adapted Ruxolitinib-Containing Regimen for the Treatment of Hemophagocytic Lymphohistiocytosis
Melissa Hines St Jude Children’s Research Hospital, Memphis, TN USA
Understanding the role of Epstein Barr virus in Hemophagocytic Lymphohistiocytosis
Principal Investigator Claire Shannon-Lowe The University of Birmingham Birmingham, United Kingdom Date of Award December 2018 Amount of…