I am...
- All
- HLH/FEL/FHL
- LCH
- Rare Histiocytic Disorders and Other Topics
The use of a newly generated murine model to determine the broad role of STXBP2 in FHL5 pathogenesis
Principal Investigator Fernando Sepulveda, Ph.D. Imagine Institute Paris, France Date of Award December 2016 Amount of Award…
HIF-1α Signaling is a Central Pathobiologic Mediator of Hemophagocytic Lymphohistiocytosis
Principal Investigator Gang Huang, Ph.D. Children’s Hospital Medical Center Cincinnati, OH USA Date of Award December 2016…
Genetic Defects in Cytolysis in Patients with Macrophage Activation Syndrome Enrolled in a Clinical Trial to Explore Interleukin-1 Blockage Therapy
Principal Investigator Randy Cron, M.D., Ph.D. University of Alabama at Birmingham Birmingham, AL USA Date of Award…
Identification of Molecular Mechanisms Underlying Defective Cytotoxic Lymphocyte Function in Chediak-Higashi Syndrome, a Histiocytic Lysosomal Storage Disorder with Immunodeficiency
Principal Investigator Konrad Krzewski, PhD National Institute of Allergy and Infectious Diseases, National Institutes of Health Rockville,…
Genetic Dissection of the Exocytic Machinery in Cytotoxic Lymphocytes
Principal Investigator Matthias Voss, PhD Karolinska Institutet Stockholm, Sweden Date of Award December 2015 Amount of…
Deciphering the Underlying Molecular Defects in CTL and NK Cell Cytotoxicity in FHL Patients
Principal Investigator Claudio Giraudo, PhD The Children’s Hospital of Philadelphia University of Pennsylvania Philadelphia, Pennsylvania USA Date…
Gaining Insights into the Mechanisms of Lymphocyte Cytotoxicity Underlying Hemophagocytic Lymphohistiocytosis
Principal Investigator Yenan Bryceson, PhD Karolinska Institutet, Stockholm, Sweden Date of Award December 2014 Amount of Award…
Comprehensive mRNA/miRNAs Expression Analysis in Familial Hemophagocytic Lymphohistiocytosis Type 2, Using the C57BL/6-Prf1tm1Sdz/J Murine Model
Principal Investigator Janos Sumegi, MD, DSc, PhD Cincinnati Children’s Hospital Medical Center, Cincinnati, OH USA Date of…
Accumulation of Heterozygous Mutations on HLH Pathogenesis
Principal Investigator Fernando Sepulveda, PhD Imagine Institute, Paris, France Date of Award December 2014 Amount of Award…
Janus Kinase Inhibition as a Novel Treatment for Hemophagocytic Lymphohistiocytosis
Principal Investigator Kim E. Nichols, MD University of Pennsylvania Perelman School of Medicine The Children’s Hospital of…