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- ECD
- HLH/FEL/FHL
- JXG
- LCH
- Rare Histiocytic Disorders and Other Topics
- RDD
Gaining Insights into the Mechanisms of Lymphocyte Cytotoxicity Underlying Hemophagocytic Lymphohistiocytosis
Principal Investigator Yenan Bryceson, PhD Karolinska Institutet, Stockholm, Sweden Date of Award December 2014 Amount of Award…
Comprehensive mRNA/miRNAs Expression Analysis in Familial Hemophagocytic Lymphohistiocytosis Type 2, Using the C57BL/6-Prf1tm1Sdz/J Murine Model
Principal Investigator Janos Sumegi, MD, DSc, PhD Cincinnati Children’s Hospital Medical Center, Cincinnati, OH USA Date of…
Accumulation of Heterozygous Mutations on HLH Pathogenesis
Principal Investigator Fernando Sepulveda, PhD Imagine Institute, Paris, France Date of Award December 2014 Amount of Award…
Janus Kinase Inhibition as a Novel Treatment for Hemophagocytic Lymphohistiocytosis
Principal Investigator Kim E. Nichols, MD University of Pennsylvania Perelman School of Medicine The Children’s Hospital of…
Gene Therapy in a Mouse Model of Virus-triggered X-linked Lymphoproliferative Disease (XLP1): Control of Infection and Disease Progression
Principal Investigator Peter Aichele, PhD University Medical Center Freiburg, University of Freiburg – Freiburg, Germany Date of…
M1 Versus M2 Polarization of the Hemophagocyte: Insight into Biologic Function
Principal Investigator Edward Behrens MD The Children’s Hospital of Philadelphia – Philadelphia, Pennsylvania USA Date of Award…
Improving Diagnostics of and Gaining Mechanistic Insights into Defects in Lymphocyte Cytotoxicity Underlying HLH
Continuation of study funded in 2011 Principal Investigator Yenan Bryceson PhD Karolinska Institutet Center for Infectious Medicine…
Focused Screening of Novel Therapies for HLH Using an Animal Model
Principal Investigator Michael Jordan MD Cincinnati Children’s Hospital Medical Center – Cincinnati, Ohio USA Date of Award…
Perforin Gene Transfer into Human Cytotoxic Lymphocytes
Principal Investigator Kimberly Risma, MD, PhD Cincinnati Children’s Hospital Medical Center – Cincinnati, Ohio USA Date of…
Mechanistic Studies of Defects in Lymphocyte Cytotoxicity Underlying HLH
Principal Investigator Yenan Bryceson PhD Karolinska Institutet Center for Infectious Medicine – Stockholm, Sweden Date of Award…