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Erdheim-Chester disease - Google News
Erdheim-Chester Disease Treatment Gets FDA Priority Review and Breakthrough Therapy Designation - Rare Disease Report

Erdheim-Chester Disease Treatment Gets FDA Priority Review and Breakthrough Therapy Designation
Rare Disease Report
The U.S. Food and Drug Administration (FDA) has accepted Genentech's supplemental New Drug Application (sNDA) and granted Priority Review for Zelboraf (vemurafenib), a therapy for patients with Erdheim-Chester disease (ECD) with a BRAF V600 ...
FDA Grants Priority Review and Breakthrough Therapy Designation for Zelboraf (vemurafenib) in Erdheim-Chester ...
FDA Grants Zelboraf Priority Review for Rare Blood Disease


Monday, August 07, 2017 10:29:49 AM

New Gene Mutations Associated with Erdheim-Chester Disease Could Improve Treatment Options - Oncology Nurse Advisor

Oncology Nurse Advisor

New Gene Mutations Associated with Erdheim-Chester Disease Could Improve Treatment Options
Oncology Nurse Advisor
Researchers identified mutations of BRAF and mutations in other MAPK pathway genes associated with Erdheim-Chester disease (ECD), according to results from a clinical trial (NCT01417520) of 60 adults with the disease.1. ECD is a very rare, potentially ...


Monday, April 10, 2017 11:01:03 AM

Genes associated with Erdheim-Chester disease also linked to cancer - Medical Xpress

Medical Xpress

Genes associated with Erdheim-Chester disease also linked to cancer
Medical Xpress
National Human Genome Research Institute (NHGRI) researchers have identified new genes associated with the Erdheim-Chester disease (ECD) and some possible new therapies. Findings on this ultra-rare disease, found in approximately 600 people in the ...


Friday, March 31, 2017 12:35:45 PM

The ultra-rare Erdheim-Chester disease: Turning grief into a campaign for a cure - Washington Post

Washington Post

The ultra-rare Erdheim-Chester disease: Turning grief into a campaign for a cure
Washington Post
The cause was Erdheim-Chester disease (ECD), one of 7,000 diseases tracked by the nonprofit National Organization for Rare Disorders. The National Institutes of Health and the Food and Drug Administration call such ailments “orphan” diseases because ...


Monday, November 17, 2014 4:47:28 PM

NORD News for April - The Voice of the Community - Rare Disease Report

Rare Disease Report

NORD News for April - The Voice of the Community
Rare Disease Report
The Running for Rare Team made an outstanding showing at the 2017 Boston Marathon, with 14 runners and a large cheering section of NORD staff and rare disease Community Partners, who are patients, caregivers and patient advocates. The team runs ...


Monday, April 24, 2017 11:41:49 PM

Somatic SNAFU—Can a Few Mutant Microglia Cause Neurodegenerative Disease? - Alzforum

Alzforum

Somatic SNAFU—Can a Few Mutant Microglia Cause Neurodegenerative Disease?
Alzforum
... the researchers investigated whether patients with histiocytoses also had abnormal microglia. They analyzed postmortem brain tissue from three patients with Erdheim-Chester disease (ECD), and conducted gene expression analysis on brain biopsies ...


Friday, September 01, 2017 5:47:32 PM

3 Things In Biotech You Should Learn Today: August 10, 2017 - Seeking Alpha

Seeking Alpha

3 Things In Biotech You Should Learn Today: August 10, 2017
Seeking Alpha
But BRAF mutations can also be associated with nonmalignant conditions, such as the inflammatory disorder called Erdheim-Chester disease (ECD). This is where the body overproduces a certain kind of white blood cell called a histiocyte, which leads to ...


Thursday, August 10, 2017 9:00:25 AM

New Genetic Insights Into Ultra-rare Disease - Technology Networks

Technology Networks

New Genetic Insights Into Ultra-rare Disease
Technology Networks
National Human Genome Research Institute (NHGRI) researchers have identified new genes associated with the Erdheim-Chester disease (ECD) and some possible new therapies. Findings on this ultra-rare disease, found in approximately 600 people in the ...


Sunday, April 02, 2017 12:07:30 PM

Is Rheumatology in a Rut? - Medscape

Medscape

Is Rheumatology in a Rut?
Medscape
If you believe the bulletins put out by the American College of Rheumatology, we have pretty much conquered all of the well-known rheumatic conditions and are now simply investigating the really uncommon ones, such as Erdheim-Chester disease or ...


Wednesday, April 05, 2017 10:01:54 AM

OncoBreak: Immunotherapy Resistance; Cancer and Opioids; Awkward Moment - MedPage Today

OncoBreak: Immunotherapy Resistance; Cancer and Opioids; Awkward Moment
MedPage Today
The FDA granted breakthrough therapy designation for the BRAF inhibitor vemurafenib (Zelboraf) for treatment of BRAF-mutant Erdheim-Chester disease, a rare condition affecting white blood cells. (Genentech). About all that excitement over immunotherapy ...


Thursday, August 10, 2017 12:49:12 PM

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